G. C. Sakellaris

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Corticotropin-releasing hormone, or factor, (CRH or CRF) exerts important biological effects in multiple peripheral tissues via paracrine/autocrine actions. The aim of our study was to assess the effects of endogenous CRH in the biology of mouse and human skin fibroblasts, the primary cell type involved in wound healing. We show expression of CRH and its(More)
AIM The complex pathobiology of traumatic brain injury (TBI) offers numerous targets for potential neuroprotective agents. We evaluate the clinical benefit after creatine (Cr) administration in children and adolescents. METHODS A prospective, randomized, comparative, open- labelled pilot study of the possible neuroprotective effect of Cr was carried out(More)
An information brokerage environment for effective information structuring, indexing, and retrieval in the health-care administration sector is presented. The system is based on ontology modeling, natural language processing, extensible markup language, semantics analysis, and behavioral description. Semantics-based information acquisition is achieved(More)
An essential cytokine system for the osteoclast biology in multiple myeloma (MM) consists of the receptor of activator of NF-κB ligand (RANKL), its receptor (RANK), and the soluble decoy receptor, osteoprotegerin (OPG). Myeloma cells cause imbalance in OPG/RANKL interactions. We measured serum levels of OPG, soluble (s) RANKL, sRANKL/OPG ratio, markers of(More)
Former graduate and 2007 recipient of the Edward T. Bryand Distinguished Engineering Award, George Sakellaris (BSEE '69) is CEO of Ameresco, Inc. which has been selected by the Department of Energy (DOE) to design and implement the nation's largest energy efficiency project in the federal government's history. The $795 million project will be located at the(More)
CITATION (Citizen Information Tool in smart administrATIONs) provides an innovative information platform for improving and promoting the provision of electronic information in the health sector, ensuring that citizens have easy and direct access to essential public data (administrative procedures, legislation and available services). The system delivers(More)
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