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BACKGROUND & OBJECTIVES Secretory phospholipase A2 (sPLA2), a member of the phospholipase A2 superfamily of enzymes that hydrolyses phospholipids, is a potentially useful plasma biomarker for atherosclerotic cardiovascular disease. Cardiovascular diseases are the leading cause of mortality in women. The purpose of this study was to investigate the(More)
BACKGROUND Adiponectin is decreased and leptin increased in overweight subjects. In turn, exercise has controversial effect upon adiponectin and leptin plasmatic levels. PURPOSE To study the effect of acute exercise upon plasmatic levels of adiponectin and leptin in normal and overweight subjects. METHOD We studied 79 subjects, 42 males and 37 females,(More)
UNLABELLED Brain natriuretic peptide (BNP) is a sensitive and specific marker of left ventricular (LV) function. The acute effect of beta blockers upon plasma BNP levels in CHF patients has been less studied but it is important because of the initial possible depressing effect upon LV function. PURPOSE To investigate the acute effect of oral Metoprolol(More)
BACKGROUND Cardiac peptides are increased at rest in heart failure patients representing a useful diagnostic tool for this condition. Recently it has been demonstrated that cardiac peptides increase also during myocardial ischemia. Cardiac peptides increase during exercise in heart failure patients, but it has not been established yet if the increase is the(More)
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