Nuclear rings are cell structures found at the nuclear cortex wedged between the nuclear envelope and the chromatin fiber network. In previous publications we have dealt with their morphology, relationships with the nuclear membranes, chromatin fibers and cytoskeletal filaments; and more recently, with their measurements at high electron microscope… (More)
In high-resolution image analysis, it is often desirable to return to a chosen cell after it has been restained or subjected to histochemical procedures. The reading of the vernier on the microscope stage is too coarse for relocating of non-distinct single cells, because the accuracy, determined by visual interpolation, is limited, at best, to 1/20th of a… (More)
This article attempts to describe the current state of quantitative cytochemical methods and to point out areas where, in the author's opinion, the greatest progress is either being made or can be expected. Nearly 300 references to the current literature are cited.