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NOTICE This document is disseminated under the sponsorship of the Department of Transportation in the interest of information exchange. The United States Government assumes no liability for its contents or use thereof. The United States Government does not endorse products or manufacturers. Trade or manufacturers' names appear herein solely because they are(More)
A highly fluorescent chiral tagging reagent, 4-(3-isothiocyanatopyrrolidin-1-yl)-7-(N,N-dimethylaminosulfonyl-2,1,3-benzoxadiazole, [R(-)-DBD-PyNCS], was employed to develop an indirect resolution method for efficient separation of thyroxine enantiomers,D-T(4) and L-T(4). The reaction of R(-)-DBD-PyNCS with the thyroxine enantiomers proceeds effectively at(More)
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