G. B. Shaposhnikova

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A new method of induction of tolerance to allogeneic and to xenogeneic cells is presented. It includes thymectomy of adult mice followed 1 month later by the injection of 1 X 10(8) spleen cells i.v. and i.p. administration of 200 mg of cyclophosphamide per kg 1 day after cells. This method induced prolonged survival of heterotopically transplanted neonatal(More)
Tolerance to allogeneic C57BL/6 (H-2b) cells was induced in CBA (H-2k mice. A combination of three types of intervention was used for tolerogenic treatment: thymectomy on adult mice, injection of a large dose of donor's spleen cells, and injection of 200 mg/kg cyclophosphamide 24 h later. Long (up to 5 months) survival of transplanted allogeneic C57BL/6(More)
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