G B Kaskey

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Two versions of the continuous performance test (CPT) differing in complexity were administered to 15 patients with bipolar affective disorder, manic type before and after treatment with lithium. Reaction time, performance accuracy, and the late positive component (LPC) of the event related potential evoked by the task were measured concurrently. Lithium(More)
Event related potentials were recorded from subjects presented with separate trains of lights and tones of three intensity levels (75, 240 and 750 fl and 60, 77 and 95 dB respectively). The auditory P1-N1 and N1-P2 components increased linearly with loudness, whereas in visual evoked responses, these components were maximal at an intermediate brightness.(More)
To examine the nature of impaired smooth pursuit eye movement (SPEM) in schizophrenia, 16 hospitalized schizophrenics in the acute phase and 16 hospitalized nonpsychotic patients were studied. The experiment consisted of five 30-sec visual tracking phases: (i) base line (no distraction); (ii) auditory-visual distraction; (iii) middle base line; (iv)(More)
To investigate the relationship between behavioral and cortical measures of impaired attention in schizophrenia, 17 hospitalized acute schizophrenics and 16 hospitalized nonpsychotic patients were studied. Event-related potentials (ERP) were obtained while subjects performed the Continuous Performance Test (CPT) under three conditions: First base line,(More)
In a retrospective study, the drug response of delusional patients with primary depression who were treated with tricyclic antidepressants (TCA), neuroleptics, or combined TCA plus neuroleptic therapy was examined. Significantly more patients responded to the combined drug regimen, as has been found in other recent studies. Clinical response was not related(More)
We have briefly covered important issues and considerations in four topic areas likely to be of use to the ERP researcher who is also interested in biological psychiatry. We cannot ignore diagnosis because of its basic role in the field of psychiatry. Although there are reliability problems, especially in the field of psychiatric diagnosis, ERPs may help in(More)
The increasing number of deinstitutionalized patients in crisis are placing new demands on general hospital emergency rooms. The authors discuss the approaches used in staffing and operating a psychiatric emergency service at a large general hospital in western Massachusetts. After studying the disposition of patients seen on the service, the authors(More)