G A Dudenhoeffer

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Muscle fiber number, cross-sectional area, and composition were studied in response to enlargement produced by synergistic ablation in the mouse soleus muscle. The effect of the location of a histological section on the number of fibers that appear in the section was also studied using the mouse soleus muscle. Enlargement was produced in the soleus muscle(More)
Chronic reduction of gravitational load in the rear limbs of rats to simulate the influence of near-zero gravity in skeletal muscles has been shown previously to elicit atrophy in the soleus muscle. Use of this model by the present investigation indicates that soleus atrophy was characterized by a decline in the number of fibers in groups that contained the(More)
In the present study, follicles were classified according to the morphology of their granulosa cells. Type B follicles contained only flattened granulosa cells; type B/C follicles had a mixture of flattened and cuboidal granulosa cells in a single layer, and type C follicles had a single layer of cuboidal granulosa cells. The primary objectives of the study(More)
The purpose of the present investigation was to determine the effects of severe dietary protein restriction on soleus (S) and tibialis anterior (TA) fiber number and S muscle fiber area, composition and length. The S and TA muscles were removed from one leg of 12 male Sprague-Dawley rats at 21 d of age. Six of these animals were placed on a 1% protein diet(More)
The primary objective of these studies was to determine whether unilateral ovariectomy (ULO) would affect rate of loss of primordial follicles. In experiment 1, retired breeder rats, unilaterally ovariectomized and maintained on the experiment for 90 days after surgery, had fewer (p less than 0.01) primordial follicles per ovary than sham-operated controls(More)
The primary objective of the present experiment was to determine if lifelong supplementation with melatonin delayed reproductive senescence through decreased loss of ovarian primordial follicles. Holtzman rats were divided into three treatments on Day 10 after pupping (Day 0 = day of pupping). Treatment 1 pups had access to water, whereas Treatment 2 and 3(More)
The purpose of this study was to determine whether or not there was a decrease in skeletal muscle fibre number in the rat from the early postnatal period to adulthood. Twelve male Sprague-Dawley rats were used in the study. At 25 days of age the animals underwent surgical removal of the soleus and tibialis anterior muscles from one hindlimb. At 180 days of(More)
The purpose of this study was to describe the soleus muscle fiber number variation within litter and within strain of three lines of laboratory rodents in an effort to determine the value of these lines in muscle fiber number research. The three lines of laboratory rodents used for the study were inbred mice (18 litters, 113 animals), outbred mice (8(More)
The effect of increased growth rate during the suckling period on subsequent body growth rate and muscle weight to body weight (MW/BW) ratio was examined in inbred and outbred male and female mice. Growth rate during the suckling period was increased by reducing litter size to 4 pups within six hours of birth. Body weight, MW/BW ratio, and dry weight to wet(More)