G. A. Antonacci

  • Citations Per Year
Learn More
We describe a new mid-infrared (mid-IR) imaging method specifically designed to augment the H + E tissue staining protocol. Images are taken with bespoke IR filters at wavelengths that enable chemical maps to be generated, corresponding to the cytoplasmic (amide) and nuclear (phosphodiester) components of unstained oesophageal tissue sections. A suitably(More)
Plaques vulnerable to rupture are characterized by a thin and stiff fibrous cap overlaying a soft lipid-rich necrotic core. The ability to measure local plaque stiffness directly to quantify plaque stress and predict rupture potential would be very attractive, but no current technology does so. This study seeks to validate the use of Brillouin microscopy to(More)
Cellular biomechanics play a pivotal role in the pathophysiology of several diseases. Unfortunately, current methods to measure biomechanical properties are invasive and mostly limited to the surface of a cell. As a result, the mechanical behaviour of subcellular structures and organelles remains poorly characterised. Here, we show three-dimensional(More)
We present the results of a measurement campaign aimed at investigating electromagnetic interference (EMI) phenomena in the interaction between overhead railway power supply lines and pantograph. In order to obtain such data, an experimental setup was assembled in a shielded room, consisting in a short section of overhead line and a full scale pantograph.(More)
The paper presents some preliminary results from numerical simulations of meteorological processes and air pollutant transport based on field measurements perfomed during winter 2006 at three target areas along the Adige Valley (Northern Italy) within the project ALPNAP, funded by the European Regional Development Fund under the initiative Interreg III B(More)
An ideal direct imaging system entails a method to illuminate on command a single diffraction-limited region in a generally thick and turbid volume. The best approximation to this is the use of large-aperture lenses that focus light into a spot. This strategy fails for regions that are embedded deep into the sample, where diffraction and scattering prevail.(More)
We experimentally demonstrate an electro-optic Gaussian-to-Bessel beam-converter miniaturized down to a 30×30  μm pixel in a potassium-lithium-tantalate-niobate (KLTN) paraelectric crystal. The converter is based on the electro-optic activation of a photoinduced and reconfigurable volume axicon lens achieved using a prewritten photorefractive funnel(More)
The authors would like to thank Prof Peter Török and Dr Carl Paterson for their advice, guidance on and contributions to the design of the microscope; Prof Török and Dr Darryl Overby for their advice and guidance on the experimental design; and Dr Overby for his advice and guidance on the development of cell protocols and sample preparation. Mr Martin Kehoe(More)
Brillouin microscopy is a non-contact and label-free technique for mapping fundamental micro-mechanical properties in the volume of biological systems. Specular reflections and elastic scattering easily overwhelm the weak Brillouin spectra due to the limited extinction of virtually imaged phased array spectrometers, thereby affecting the image acquisition.(More)
  • 1