In the tripartite model of working memory (WM) it is postulated that a unique part system-the visuo-spatial sketchpad (VSSP)-processes non-verbal content. Due to behavioral and neurophysiological findings, the VSSP was later subdivided into visual object and visual spatial processing, the former representing objects' appearance and the latter spatial… (More)
We compared spatial short-term memory for visual and auditory stimuli in an event-related slow potentials study. Subjects encoded object locations of either four or six sequentially presented auditory or visual stimuli and maintained them during a retention period of 6 s. Slow potentials recorded during encoding were modulated by the modality of the… (More)
A series of experiments compared short-term memory for object locations in the auditory and visual modalities. The stimulus materials consisted of sounds and pictures presented at different locations in space. Items were presented in pure- or mixed-modality lists of increasing length. At test, participants responded to renewed presentation of the objects by… (More)
The distribution and dendritic morphology of neurons in the cat pretectal nuclear complex were analyzed with respect to their projection to the ipsilateral dorsal lateral geniculate nucleus (LGNd) and the ipsilateral inferior olive (IO). Single and double retrograde tracing techniques were combined with intracellular injections of either horseradish… (More)
If configurations of objects are presented in a S1-S2 matching task for the identity of objects a spatial mismatch effect occurs. Changing the (irrelevant) spatial layout lengthens response times. We investigated what causes this effect. We observed a reliable mismatch effect that was not influenced by a secondary task during maintenance. Neither… (More)
Vinyl chloride (VC) is a know animal and human carcinogen associated with liver angiosarcomas (LAS) and hepatocellular carcinomas (HCC). In VC-associated LAS mutations of the K- ras -2 gene have been reported; however, no data about the prevalence of such mutations in VC associated HCCs are available. Recent data indicate K- ras -2 mutations induce P16… (More)
Two cross-sectional studies were conducted at a German aluminum (Al) powder plant to evaluate possible nervous system effects from occupational Al exposure. The investigation included biological monitoring, a neuropsychological test battery, and event-related P300 potentials. Neurophysiologic findings in workers chronically exposed to Al dust did not differ… (More)
Untersuchungen über leistungsbegrenzende Bedingungen bei einer optischen Kontrollaufgabe. Desynchronization of different physiological functions during three weeks of experimental nightshift with limited and unlimited sleep.