Gülmisal Güder

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BACKGROUND The Global initiative for chronic Obstructive Lung Disease (GOLD) defines COPD as a fixed post-bronchodilator ratio of forced expiratory volume in 1 second and forced vital capacity (FEV1/FVC) below 0.7. Age-dependent cut-off values below the lower fifth percentile (LLN) of this ratio derived from the general population have been proposed as an(More)
BACKGROUND The maximal expiratory flow at 50 % of the forced vital capacity (MEF50) is the flow where half of forced vital capacity (FVC) remains to be exhaled. A reduced MEF50 has been suggested as a surrogate marker of small airways disease. The diagnostic and prognostic utility of this easy to assess spirometric variable in persons with respiratory(More)
It is a very refreshing idea to use clinical data and health outcomes to decide how to best diagnose Chronic Obstructive Pulmonary Disease (COPD). Therefore we read the article by Güder et al. [1] with great interest. However, upon reading the article in more detail we developed reservations about the criteria used. The authors started with 405 patients(More)
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