Gérard Krause

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BACKGROUND We describe an outbreak of gastroenteritis and the hemolytic-uremic syndrome caused by Shiga-toxin-producing Escherichia coli in Germany in May, June, and July, 2011. The consumption of sprouts was identified as the most likely vehicle of infection. METHODS We analyzed data from reports in Germany of Shiga-toxin-producing E. coli(More)
BACKGROUND A large outbreak of the hemolytic-uremic syndrome caused by Shiga-toxin-producing Escherichia coli O104:H4 occurred in Germany in May 2011. The source of infection was undetermined. METHODS We conducted a matched case-control study and a recipe-based restaurant cohort study, along with environmental, trace-back, and trace-forward(More)
BACKGROUND The quantification of the burden of disease attributable to hepatitis B virus (HBV) infection and the adaptation of prevention and control measures requires knowledge on its prevalence in the general population. For most countries such data are not routinely available. We estimated the national, regional, and global prevalence of chronic HBV(More)
INTRODUCTION To establish strategic priorities for the German national public health institute (RKI) and guide the institute's mid-term strategic decisions, we prioritized infectious pathogens in accordance with their importance for national surveillance and epidemiological research. METHODS We used the Delphi process with internal (RKI) and external(More)
†Maria D Van Kerkhove1,2 Katelijn AH Vandemaele1, Vivek Shinde1, Giovanna Jaramillo-Gutierrez,1 Artemis Koukounari,2 Christl Donnelly,2 Luis O. Carlino,3 Rhonda Owen,4 Beverly Paterson,4 Louise Pelletier,5 Julie Vachon,5 Claudia Gonzalez,6 Yu Hongjie,7 Feng Zijian,7 Shuk Kwan Chuang,8 Albert Au,8 Silke Buda,9 Gerard Krause,9 Walter Haas,9 Isabelle(More)
During the 2009 influenza pandemic, a monovalent AS03-adjuvanted vaccine was almost exclusively used in Germany for immunisation against the 2009 pandemic influenza A(H1N1) virus. One-dose vaccination was recommended for all age groups. We applied the screening method for the rapid assessment of vaccine effectiveness (VE) based on reported data of(More)
Since early May 2011, an increased incidence of haemolytic uraemic syndrome (HUS) and bloody diarrhoea related to infections with Shiga toxin-producing Escherichia coli (STEC) has been observed in Germany, with most cases in the north of the country. Cases reported from other European countries had travelled to this area. First results of a case–control(More)
In 2001 Germany implemented a new electronic reporting system for surveillance of notifiable infectious diseases (SurvNet@RKI). The system is currently being used in all 431 local health departments (LHD), the 16 state health departments (SHD) and the Robert Koch-Institut (RKI), the national agency for infectious disease epidemiology. The SurvNet@RKI(More)
In 2001, the Robert Koch Institute (RKI) implemented a new electronic surveillance system (SurvNet) for infectious disease outbreaks in Germany. SurvNet has captured 30,578 outbreak reports in 2001-2005. The size of the outbreaks ranged from 2 to 527 cases. For outbreaks reported in 2002-2005, the median duration from notification of the first case to the(More)
Neue Infektionskrankheiten haben sich teils auch in Deutschland ausgebreitet, teils sind sie auf bestimmte Regionen der Welt begrenzt und begegnen dem Arzt nur, wenn Reisende sich in diesen Gebieten infizieren und die Krankheiten sich nach der Rückkehr manifestieren. HIV ist ein Beispiel für einen importierten, inzwischen endemischen Erreger. SARS und die(More)