Gérard Duru

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BACKGROUND Depression is among the major contributors to worldwide disease burden and adequate modelling requires a framework designed to depict real world disease progression as well as its economic implications as closely as possible. OBJECTIVES In light of the specific characteristics associated with depression (multiple episodes at varying intervals,(More)
Cognitive dysfunction is increasingly recognized as a symptom in mental conditions including schizophrenia, major depressive disorder (MDD), and bipolar disorder (BPD). Despite the many available cognitive assessment instruments, consensus is lacking on their appropriate use in clinical trials. We conducted a systematic literature review in Embase,(More)
OBJECTIVE To develop a new quality-of-life (QoL) instrument with international validity that specifically assesses cosmetic products and physical appearance. DESIGN In the first phase, semidirected interviews involved 309 subjects. In the second stage, an acceptability study was performed on 874 subjects. Thereafter, we recruited a total of 3231 subjects,(More)
Health authorities are constantly searching for new ways to stabilise health expenditures. To explore this issue, we compared the costs generated by different types of medical practice in French general medicine: i.e. conventional (CM-GP), homeopathic (Ho-GP), or mixed (Mx-GP).Data from a previous cross-sectional study, EPI3 La-Ser, were used. Three types(More)
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