In 131 patients treated exclusively by selective denervation during the past 10 years, all or almost all the abnormal movements of spasmodic torticollis were suppressed in 115 (88%) while preserving posture and mobility. This approach was also used in certain forms of adult-onset dystonia. An appreciable amount of abnormal movements remained in the other… (More)
In two cases, depth electrode studies and behavioral recordings indicated that headache was a clinical manifestation of ictal activity. The epileptogenic focus was found in the right limbic system, and right temporal lobectomy relieved the headaches.
We studied 24 patients who had adversion as the first clinical manifestation of seizures. Seizures were recorded with depth electrodes as part of the evaluation for possible surgery for epilepsy. Head rotation did not help to lateralize the epileptic focus clinically, because deviations occurred ipsilaterally to the EEG focus in some patients, and because… (More)
We examined the hypothesis of dorsomedial frontal lobe involvement in target detection through the effects of distractor interference and multiple target interference on unilateral lobectomy patients. Seven patients who underwent a unilateral frontal lobectomy for epilepsy involving dorsomedial cortex and variable amounts of lateral cortex were compared to… (More)
Chronic depth electrodes have proven useful in diagnosing primary epilepsy of the limbic system. Five patients had small lesions in the amygdala and hippocampus. There was a 50% reduction of the seizures frequency. No complication were observed and patients were ambulant the day following surgery. It is felt that stereotactic lesions larger than produced by… (More)
We examined the somatosensory perceptions evoked by stimulation of rolandic and parietal brain regions in 40 epileptic patients undergoing a presurgical investigation with intracerebral electrodes. Bipolar stimulation trains were delivered in an incremental sequence at medial and/or lateral contact pairs of stereotaxically implanted, multi-contact… (More)
A recurrent malignant glioma was treated with cisplatin delivered directly into the tumor. The drug was delivered via 68 small catheters distributed evenly throughout the tumor area. Each catheter was connected to an osmotic minipump that delivered 0.5 microliter of drug solution each hour for 10 days. There were no side effects from the catheter… (More)
Intracerebral auditory evoked potentials were recorded from multi-contact electrodes chronically implanted in frontal, temporal, and parietal regions of the brains of 10 epileptic patients. Binaurally presented tones produced a large widely distributed biphasic potential with a close latency correspondence to the scalp vertex response. In each hemisphere,… (More)