Learn More
We describe a conservative, shock-capturing scheme for evolving the equations of general relativistic magnetohydrodynamics. The fluxes are calculated using the Harten, Lax, and van Leer scheme. A variant of constrained transport, proposed earlier by Tóth, is used to maintain a divergence free magnetic field. Only the covariant form of the metric in a(More)
Pituitary adenylate cyclase activating popypeptide (PACAP) is a pleiotropic neuropeptide, exerting neurotrophic and neuroprotective effects in numerous models of in vitro and in vivo nervous injuries. The aim of the present study was to investigate whether PACAP is neuroprotective in ischemic retinal damage. Adult male Wistar rats underwent bilateral(More)
  • Ward B Manchester, Iv, Tamas I Gombosi, Ilia Roussev, Aaron Ridley, Darren L De Zeeuw +10 others
  • 2004
[1] We present a three-dimensional (3-D) numerical ideal magnetohydrodynamics (MHD) model describing the time-dependent expulsion of a coronal mass ejection (CME) from the solar corona propagating to 1 astronomical unit (AU). The simulations are performed using the Block Adaptive Tree Solar-Wind Roe Upwind Scheme (BATS-R-US) code. We begin by developing a(More)
Several in vitro and in vivo experiments have demonstrated the neuroprotective effects of pituitary adenylate cyclase activating polypeptide (PACAP) in focal cerebral ischemia, Parkinson's disease and traumatic brain injury (TBI). The aim of the present study was to analyze the effect of PACAP administration on diffuse axonal injury (DAI), an important(More)
Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors are present in the retina and exert several distinct functions. PACAP has well-known neuroprotective effects in neuronal cultures in vitro and against different insults in vivo. Recently we have shown that PACAP is neuroprotective against monosodium glutamate (MSG)-induced retinal(More)
The neuropeptide PACAP (pituitary adenylate cyclase activating polypeptide) and its receptors are widely expressed in the nervous system including the retina. PACAP has well-known neuroprotective effects in neuronal cultures in vitro and against different insults in vivo. Recently, we have shown that PACAP1-38 is neuroprotective against monosodium glutamate(More)
[1] The Space Weather Modeling Framework (SWMF) provides a high-performance flexible framework for physics-based space weather simulations, as well as for various space physics applications. The SWMF integrates numerical models of the Solar Corona, Upper Atmosphere into a high-performance coupled model. The components can be represented with alternative(More)
Pituitary adenylate cyclase activating polypeptide (PACAP) has been shown to be neuroprotective in retinal ischemia and monosodium L-glutamate (MSG)-induced retinal degeneration. Here we describe how different MSG treatments (1x and 3x application) cause retinal damage and finally lead to the destruction of the entire inner retina and how PACAP attenuates(More)