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Severe fever with thrombocytopenia syndrome bunyavirus is a newly discovered bunyavirus with high pathogenicity to human. The transmission model has been largely uncharacterized. Investigation on a cluster of severe fever with thrombocytopenia syndrome cases provided evidence of person-to-person transmission through blood contact to the index patient with(More)
BACKGROUND The incidence of dengue, an infectious disease caused by dengue virus (DENV), has dramatically increased around the world in recent decades and is becoming a severe public health threat. However, there is currently no specific treatment for dengue fever, and licensed vaccine against dengue is not available. Vaccination with virus-like particles(More)
To improve the searching ability and convergence speed of differential evolution (DE), we combined a search operation for enhancing the performance of the original DE. The simplified quadratic interpolation (SQI) is employed to improve the local search ability and the accuracy of the minimum function value, and to reduce greatly the computational overhead(More)
BACKGROUND SFTS virus (SFTSV) is a newly discovered pathogen to cause severe fever with thrombocytopenia syndrome (SFTS) in human. Successful control of SFTSV epidemic requires better understanding of the antigen target in humoral immune responses to the new bunyavirus infection. METHODOLOGY/PRINCIPAL FINDINGS We have generated a combinatorial Fab(More)
This paper presents design, analysis, and experiment of the feed cable-suspended structure for the next generation large spherical radio telescope. To begin with, considering the requirement of the orientation of the feed cable-suspended structure increased to 60deg from 40deg, optimization design of the structure is performed. Then, aiming at the drawback(More)
We present the design and experimental demonstration of a magnetic screen, which can pattern magnetic field into 256 programmable spots of small sub-wavelength dimension. A design methodology is outlined for designing a near-field plate to achieve a desired focus, and its implementation is discussed. Simulation using a full-wave electromagnetic solver(More)
This paper presents a global optimization method based on the statistical genetic algorithm for solving nonlinear bilevel programming problems. The bilevel programming problem is firstly transformed into a single level problem by applying Karush-Kuhn-Tucker conditions, and then an efficient method based on the statistical genetic algorithm has been proposed(More)
A dual-band (915–935MHz and 1760–1805MHz) Yagi-Uda antenna with branch structures is proposed. The parameters of the branch structure are optimized to obtain the antenna that operates perfectly in the two bands. Prototype is fabricated and measured, and the results are in good agreement with the simulated ones. The presented antenna achieves(More)
Enterovirus 71 (EV71) is the etiologic agent of hand-foot-and-mouth disease (HFMD) in the Asia-Pacific region, Many strategies have been applied to develop EV71 vaccines but no vaccines are currently available. Mucosal immunization of the VP1, a major immunogenic capsid protein of EV71, may be an alternative way to prevent EV71 infection. In this study,(More)