Fushan Song

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Differential display (DD) is widely employed for identifying uniquely expressed genes within two different cell populations. While potentially powerful, DD is problematic because apparent positive clones require time-consuming verification which may be made even more difficult if only small amounts of starting material are available. We have devised a(More)
MOTIVATION An important class of protein interactions involves the binding of a protein's domain to a short linear motif (SLiM) on its interacting partner. Extracting such motifs, either experimentally or computationally, is challenging because of their weak binding and high degree of degeneracy. Recent rapid increase of available protein structures(More)
  • Fushan Song
  • Zhongguo yi xue ke xue yuan xue bao. Acta…
  • 1996
Since the first report on the use of mutants lacking enzymes and HAT medium for hybrid selection (Littlefield, 1964), enormous similar techniques, at least, have been basically established. These techniques have opened new avenues to assigning genes, analysing gene regulation in eukaryotic cells and studying mechanisms which govern cell growth and(More)
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