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  • Fumiko Obata, Koujiro Tohyama, +6 authors Tom G. Obrig
  • Chemistry, Biology, Medicine
  • The Journal of infectious diseases
  • 2008 (First Publication: 1 November 2008)
  • Affinity-purified Shiga toxin (Stx) 2 given intraperitoneally to mice caused weight loss and hind-limb paralysis followed by death. Globotriaosylceramide (Gb(3)), the receptor for Stx2, was localizedContinue Reading
  • Samuel M. Stone, Cheleste M Thorpe, +7 authors Dakshina M. Jandhyala
  • Biology, Medicine
  • Front. Cell. Inf. Microbio.
  • 2012 (First Publication: 8 November 2012)
  • Shiga toxin producing Escherichia coli (STEC) are a major cause of food-borne illness worldwide. However, a consensus regarding the role Shiga toxins play in the onset of diarrhea and hemorrhagicContinue Reading
  • Fumiko Obata, Lauren M. Hippler, Progyaparamita Saha, Dakshina M. Jandhyala, Olga S. Latinovic
  • Medicine, Biology
  • Front. Mol. Neurosci.
  • 2015 (First Publication: 14 July 2015)
  • Shiga toxin-producing Escherichia coli (STEC) can cause central nervous system (CNS) damage resulting in paralysis, seizures, and coma. The key STEC virulence factors associated with systemic illnessContinue Reading