Fumihiko Ichikawa

We don’t have enough information about this author to calculate their statistics. If you think this is an error let us know.
Learn More
Assurance of surface glossiness is one of the most important factors in the production of stainless steel strips, but the surface glossiness has been evaluated by off-line measurement and visual inspection. For the purpose of on-line evaluation of the surface glossiness, an optical measurement method of the surface glossiness and a neural network-based(More)
Untreated latent fingerprints are known to exhibit fluorescence under UV laser excitation. Previously, the hyperspectral imager (HSI) has been primarily evaluated in terms of its potential to enhance the sensitivity of latent fingerprint detection following treatment by conventional chemical methods in the forensic science field. In this study however, the(More)
Novel vitamin D(3) analogs with carboxylic acid were explored, focusing on a nonsecosteroidal analog, LG190178, with a bisphenyl skeleton. From X-ray analysis of these analogs with vitamin D receptor (VDR), the carboxyl groups had very unique hydrogen bonding interactions in VDR and mimicked 1α-hydroxy group and/or 3β-hydroxy group of 1α,25-dihydroxyvitamin(More)
  • Hirotaka Kashiwagi, Yoshiyuki Ono, +7 authors Tadakatsu Takahashi
  • Bioorganic & medicinal chemistry
  • 2013
In an extension of our study on gamma hydroxy carboxylic acid analogs, we explored a series of nonsecosteroidal vitamin D receptor (VDR) agonists in which 1,3-diol of 1,25(OH)2D3 had been replaced by aryl acetic acid. These analogs showed very potent activity in vitro compared with 1,25(OH)2D3. An X-ray analysis of 8d showed that the inserted phenyl ring(More)
BACKGROUND Since Slatopolsky et al. (J Clin Invest 1984; 74: 2136-2143) reported the effect of active vitamin D, 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), on secondary hyperparathyroidism (2HPT) which accompanies chronic renal failure, there have been several studies of the therapeutic effects of 1,25(OH)(2)D(3) in this disease. Although parathyroid(More)
  • 1