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OBJECTIVES We sought to evaluate the safety, efficacy, and feasibility of endoscopic sphincterotomy plus large balloon dilation (ESLBD) and to compare procedural time and fluoroscopy time of ESLBD with those of endoscopic sphincterotomy (EST) alone for patients with large bile duct stones. METHODS Retrospective analysis. RESULTS A total of 101 patients(More)
BACKGROUND/PURPOSE It has been reported that circulating tumor cells (CTCs) can be used to predict survival in metastatic breast cancer. In this preliminary study, we examined the level of CTCs in pancreatic cancer (PC) patients to elucidate whether we could predict survival in PC. METHODS The eligible subjects, at Tokyo Medical University Hospital, were(More)
OBJECTIVES The aim of this study was to evaluate the usefulness of single-balloon enteroscopy (SBE)-assisted endoscopic retrograde cholangiopancreatography (ERCP) in patients with Billroth II gastrectomy (B-II) or Roux-en-Y anastomosis (R-Y). METHODS Thirteen SBE procedures were performed in 2 patients with B-II and 11 patients with R-Y at Tokyo Medical(More)
BACKGROUND Endoscopic ultrasonography (EUS)-guided pancreatic drainage has been advocated as a rescue treatment for management of patients in whom retrograde access to the pancreatic duct (PD) is technically unsuccessful. The aim of the present study was to evaluate the feasibility and efficacy of EUS-guided drainage for failed endoscopic retrograde(More)
BACKGROUND AND AIM In patients with Roux-en-Y hepaticojejunostomy (HJ with R-Y) and Whipple resection, endoscopic retrograde cholangiopancreatography (ERCP) can be challenging. We report our experience with ERCP using balloon-assisted enteroscopy (BAE) (BAE-ERCP) in patients with HJ with R-Y, and Whipple resection. METHODS BAE-ERCP procedures were carried(More)
BACKGROUND Gemcitabine is an efficacious cytotoxic agent used in the treatment of unresectable pancreatic carcinoma (PC). Recently, gemcitabine resistance has been associated with the ribonucleotide reductase subunit M2 (RRM2). In this prospective study, we hypothesized that RRM2 expression in PC biopsy specimens would be a significant predictor of outcome.(More)
BACKGROUND Pancreatodigestive tract anastomotic site stenosis is a problematic complication after pancreatoduodenectomy. OBJECTIVE We evaluated the feasibility and efficacy of endoscopic treatments for a stenotic pancreatodigestive tract anastomosis. DESIGN Retrospective study. SETTING Endoscopic units of a university-affiliated hospital and a general(More)
We evaluated the usefulness of peroral cholangioscopy (POCS) for residual bile duct stones in patients with complete bile duct clearance confirmed by balloon-occluded cholangiography. A total of 108 patients with common bile duct stones who underwent POCS after extraction of stones via endoscopic sphincterotomy, resulting in complete bile duct extraction(More)