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Safety of the long-acting neuraminidase inhibitor laninamivir octanoate hydrate in post-marketing surveillance.
TLDR
It was confirmed that laninamivir is unlikely to cause delayed ADRs or a prolonged duration of ADRs despite this drug being a long-acting NAI and the types of ADR observed were similar to those previously observed. Expand
Clinical efficacy of long-acting neuraminidase inhibitor laninamivir octanoate hydrate in postmarketing surveillance
TLDR
Despite laninamivir requiring only the administration of a single dose, it was confirmed to be an effective treatment in more than 90 % of patients with type A or type B influenza virus infections. Expand
[Study on the safety and efficacy of sitafloxacin--results of the use-results survey].
TLDR
This use-results survey confirmed that STFX is a useful antibacterial agent with no serious problems in its safety profile and efficacy rates of over 90% against all infections. Expand
Post-marketing surveillance (PMS) of all patients treated with irinotecan in Japan: clinical experience and ADR profile of 13,935 patients.
TLDR
It was reconfirmed that the incidences of serious leukopenia, thrombocytopenia and diarrhea were high among the patients with contraindication or careful administration of its use prescribed in the drug package insert, and it is important to discriminate the patient on the basis of risk status. Expand
Peptide synthesis in water IV. Preparation of N-ethanesulfonylethoxycarbonyl (Esc) amino acids and their application to solid phase peptide synthesis.
TLDR
A new N-protecting group, ethanesulfonylethyl-4-nitrophenyl carbonate (Esc), was designed to perform peptide synthesis in both aqueous and organic solvents and was successfully synthesized on a poly(ethylene glycol)-grafted polystyrene resin. Expand
Separation of amino acids and proteins by electrically enhanced membrane filtrations
Separation of protein mixtures and amino acid mixtures by electrically enhanced ultrafiltration (EUF) and microfiltration (EMF) was studied. EUF and EMF are new membrane separation processes combinedExpand
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