OBJECTIVE
To assess the influence of aging, blood pressure, and body mass index (BMI) on intraocular pressure (IOP) in a large Japanese population.
DESIGN
Cross-sectional and longitudinal study.
… (More)
PURPOSE
Previous cross-sectional Japanese studies have shown that intraocular pressure (IOP) decreases with age. However, central corneal thickness (CCT) variation should also be considered when… (More)
Given that osteoprotegerin plays an important role in bone remodeling, the osteoprotegerin gene may be a candidate locus for susceptibility to osteoporosis. The relation of polymorphisms in the… (More)
PURPOSE
To investigate the refractive status and factors associated with myopia by a population-based survey of Japanese adults.
METHODS
A total of 2168 subjects aged 40 to 79 years, randomly… (More)
Magnesium (Mg) deficiency is believed to have adverse cardiovascular consequences that are broad and complex, although an association between dietary Mg intake and the risk of coronary heart disease… (More)
OBJECTIVE
To examine whether polymorphisms of the estrogen receptor (ER) alpha gene are associated with body fat distribution.
DESIGN
Cross-sectional, epidemiological study of two single-nucleotide… (More)
The estrogen receptor α gene is a candidate locus for genetic influence on bone mass. The possible association between two polymorphisms in the first intron of this gene, alone or in combination, and… (More)
Ultrasonic evaluation of the intima-media thickness in the common carotid artery (IMT-CCA) has been widely used as a marker of atherosclerosis. However, the definition of IMT-CCA is not uniform and… (More)
AbstractOxidative stress may affect cellular functions in various pathological conditions, including osteoporosis. Paraoxonase 1 confers antioxidant properties on high-density lipoprotein, with which… (More)
Recent epidemiological studies show the associations of serum antioxidant status with the metabolic syndrome. Oxidative stress may play an important role in the pathogenesis of diabetes and CVD.… (More)