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Many previous neuroimaging studies have shown that the early visual cortex of the early blind (EB) exhibits significant functional plasticity. However, only few previous studies have addressed the question whether or not such functional plasticity is accompanied by, and even related to, structural plasticity. In this study, we acquired high-resolution(More)
BACKGROUND Internet addiction disorder (IAD) is currently becoming a serious mental health issue around the globe. Previous studies regarding IAD were mainly focused on associated psychological examinations. However, there are few studies on brain structure and function about IAD. In this study, we used diffusion tensor imaging (DTI) to investigate white(More)
BACKGROUND Abnormal macrostructural brain abnormalities in both gray matter and white matter have been reported in cigarette smokers. However, less is known about white matter microstructure in heavy cigarette smokers. In this study, we used diffusion tensor imaging (DTI) to investigate the integrity of the white matter microstructure in heavy smokers. (More)
BACKGROUND This study aims to investigate brain gray matter density (GMD) changes in adolescents with Internet addiction (IA) using voxel-based morphometry (VBM) analysis on high-resolution T1-weighted structural magnetic resonance images. METHODS Eighteen IA adolescents and 15 age- and gender-matched healthy controls took part in this study.(More)
In this study, we introduced a length-normalized parameterization method to establish anatomical correspondence of white matter fiber tracts across subjects and applied this method to investigate the presence of abnormal diffusion along the pyramidal tract (PYT) of relapsing neuromyelitis optica (RNMO) patients without visible brain lesions. In this(More)
PURPOSE To prospectively evaluate diffusion indexes of the corticospinal tract (CST), corpus callosum (CC), optic radiation (OR), and cingulum in patients with neuromyelitis optica (NMO) without visible lesions in the brain. MATERIALS AND METHODS All participants provided informed consent, and the study was approved by the institutional review board.(More)
Recent neuroimaging studies have demonstrated that cigarette smoking is associated with changed brain structure and function. However, little is known about alterations of the topological organization of brain functional networks in heavy smokers. Thirty-one heavy smokers and 33 non-smokers underwent a resting-state functional magnetic resonance imaging(More)
OBJECTIVE In bipolar disorder, white matter abnormalities have been reported with region-of-interest and voxel-based methods; however, deficits in specific white matter tracts cannot be localized by these methods. Therefore, in this study, we aimed to investigate the white matter tracts that mediate connectivity of the frontal cortex using diffusion tensor(More)
Abnormal structure and function in the striatum and prefrontal cortex (PFC) have been revealed in Internet addiction disorder (IAD). However, little is known about alterations of corticostriatal functional circuits in IAD. The aim of this study was to investigate the integrity of corticostriatal functional circuits and their relations to neuropsychological(More)
BACKGROUND To investigate nerve fibre damage of the visual pathway in patients with primary open-angle glaucoma using tract-based spatial statistical analysis of diffusion tensor imaging and correlate these measures with the clinical severity of glaucoma. DESIGN Cross-sectional study. PARTICIPANTS Twenty-five individuals with primary open-angle glaucoma(More)