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In 1982, R.Wille proposed a new model to represent the formal concepts associated to a context (G,M, I), named formal concept analysis based on formal context, which is a binary relation between a set of objects and a set of attributes. The main goal is to reveal the hierarchical structure of formal concepts and to investigate the dependencies among(More)
BACKGROUND & AIMS Nilotinib is a novel tyrosine kinase inhibitor of Bcr-Abl and other kinases. In this study, we have examined its activity as an anti-fibrotic agent. METHODS The in vitro effect of Nilotinib on rat and human HSCs was assessed using proliferation assays and Western blotting. The in vivo antifibrotic efficacy of Nilotinib was assessed in(More)
A series of novel imidazo[1,5-a]pyridine-hydrazone derivatives were synthesized and characterized by infrared spectroscopy (IR), 1H NMR, 13C NMR and high resolution mass spectrometer (HRMS). Typically, the spatial structure of compound 3j was determined using X-ray diffraction analysis. The UV-vis absorption and fluorescence spectral characteristics of the(More)
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