Ft Mcpherson

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We have investigated the regulation of p27kip1, a cyclin-dependent kinase inhibitor, in BALB/c 3T3 cells during growth factor-stimulated transition from quiescence (G0) to a proliferative (G1) state. The level of p27kip1 protein falls dramatically after mitogenic stimulation and is accompanied by a decrease in cyclin E associated p27kip1, as well as a(More)
The effectiveness was compared of 'Classroom' Reality Orientation presented (1) once daily, in groups; (2) twice daily, in groups; and (3) once daily, individually. On a questionnaire measure of orientation all three versions produced significantly greater improvement than that found in an untreated control group, but did not differ in their relative(More)
Six groups were tested: 20 depressed, 10 manic, 10 schizophrenic, 10 alcoholic and 10 physically ill patients, and 10 recovered depressed patients. They were administered repertory grids whose 10 elements were role titles and which employed 12 elicited constructs and one provided construct. After principal component analysis of each grid, measures were(More)
To test the Foulds and Bedford hierarchical model of personal illness, the Delusions-Symptoms-States Inventory (DSSI) was administered to 100 psychiatric in-patients. Ninety-six had symptom patterns compatible with the hierarchy. This is significantly more than expected on the basis merely of the number of DSSI items affirmed, and overall the results(More)
The concurrent validity of the survey version of the Clifton Assessment Procedures for the Elderly (CAPE) was assessed by comparing the performance of four groups of elderly women selected to represent different levels of impairment and dependency. It was found to discriminate significantly among patients with severe (n = 100), moderate (n = 40), mild (n =(More)
Sixteen of the depressed patients and nine of the manic patients, who were studied by Ashworth et al. (1982), were retested after clinical recovery. As on the previous occasion, each patient completed a repertory grid whose 10 elements were role titles and which employed 12 elicited constructs and one provided construct. After principal component analysis(More)