Friederike Dündar

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We present a Galaxy based web server for processing and visualizing deeply sequenced data. The web server's core functionality consists of a suite of newly developed tools, called deepTools, that enable users with little bioinformatic background to explore the results of their sequencing experiments in a standardized setting. Users can upload pre-processed(More)
We present an update to our Galaxy-based web server for processing and visualizing deeply sequenced data. Its core tool set, deepTools, allows users to perform complete bioinformatic workflows ranging from quality controls and normalizations of aligned reads to integrative analyses, including clustering and visualization approaches. Since we first described(More)
Histone acetyl transferases (HATs) play distinct roles in many cellular processes and are frequently misregulated in cancers. Here, we study the regulatory potential of MYST1-(MOF)-containing MSL and NSL complexes in mouse embryonic stem cells (ESCs) and neuronal progenitors. We find that both complexes influence transcription by targeting promoters and(More)
Proper gene expression requires coordinated interplay among transcriptional coactivators, transcription factors and the general transcription machinery. We report here that MSL1, a central component of the dosage compensation complex in Drosophila melanogaster and Drosophila virilis, displays evolutionarily conserved sex-independent binding to promoters.(More)
MOF-associated complexes ensure stem cell identity and Xist repression Thomas Manke, Asifa Akhtar Ramírez, Anne-Valerie Gendrel, Patrick R Wright, Pavankumar Videm, Rolf Backofen, Edith Heard, Tomasz Chelmicki, Friederike Dündar, Matthew Turley, Tasneem Khanam, Tugce Aktas, Fidel http://dx.doi.org/10.7554/eLife.02024 DOI: Cite as: eLife(More)
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