The generation and release of lipoxygenase factors and leukotrienes from human polymorphonuclear granulocytes is demonstrated during bacterial phagocytosis and interaction with bacterial exotoxins… (More)
Effects of Staphylococcus aureus alpha-toxin and Pseudomonas aeruginosa cytotoxin on the permeability of an endothelial monolayer were studied. Porcine pulmonary artery endothelial cells were grown… (More)
Toxicon : official journal of the International…
1994
The effect of Pseudomonas aeruginosa cytotoxin was assessed in leukopenic outbred Swiss male mice (20 g) using a high cytotoxin-producing strain (PA158) and its cytotoxin-deficient isogenic mutant… (More)
The effect of Pseudomonas aeruginosa cytotoxin on human granulocytes (PMNs) and pooled human serum was studied by hemacytometer counts, phagocytic, bactericidal, and chemotaxis assays, and by… (More)
Ehrlich ascites tumor cells from mice were damaged during in vitro incubation with a cytotoxin from Pseudomonas aeruginosa at concentrations of>1 μg/ml. After a short time the cells started to lose… (More)
Toxicon : official journal of the International…
1987
Increased plasma membrane permeability induced by a purified cytotoxic protein from Pseudomonas aeruginosa was studied using mouse Ehrlich ascites tumor cells in incubation medium containing an… (More)
Toxicon : official journal of the International…
1989
A cytotoxic protein isolated from Pseudomonas aeruginosa damages the plasma membranes of many mammalian cells by forming pores. We studied binding of the 125I-cytotoxin and the resulting increase of… (More)
0728 02 1. Double perfusion experiments with isolated rat livers confirm our earlier hypothesis that phalloidin activates a cytotoxic principle in the poisoned liver. 2. After absorption of the… (More)