Frederik M Meyer

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We documented the risks associated with windsurfing on sewage polluted water. Seventy-nine windsurfers and 41 controls were studied over a nine-day period for occurrence of symptoms of gastroenteritis, otitis, conjunctivitis, and skin infection. Relative risks were 2.9 for occurrence of one or more of these symptoms and 5.5 for symptoms of gastroenteritis.(More)
In Bacillus subtilis, recent in vivo studies revealed that particular enzymes of the tricarboxylic acid cycle form complexes that allow an efficient transfer of metabolites. Remarkably, a complex of the malate dehydrogenase (Mdh) (EC 1.1.1.37) with isocitrate dehydrogenase (Icd) (EC 1.1.1.42) was identified, although both enzymes do not catalyze subsequent(More)
The majority of all proteins of a living cell is active in complexes rather than in an isolated way. These protein-protein interactions are of high relevance for many biological functions. In addition to many well established protein complexes an increasing number of protein-protein interactions, which form rather transient complexes has recently been(More)
The Gram-positive soil bacterium Bacillus subtilis uses glucose and malate as the preferred carbon sources. In the presence of either glucose or malate, the expression of genes and operons for the utilization of secondary carbon sources is subject to carbon catabolite repression. While glucose is a preferred substrate in many organisms from bacteria to man,(More)
Most organisms can choose their preferred carbon source from a mixture of nutrients. This process is called carbon catabolite repression. The Gram-positive bacterium Bacillus subtilis uses glucose as the preferred source of carbon and energy. Glucose-mediated catabolite repression is caused by binding of the CcpA transcription factor to the promoter regions(More)
A case-control study was conducted in Quebec elderly men in order to document the risk of road accidents associated with impairments or chronic medical conditions. All 1,400 drivers who had had an accident with either mild bodily injury or only property damage during their 70th year in 1988 and 1989 were selected as cases from the accident file of the(More)
To document the risk of road accidents associated with minimal visual acuity (equal to 6/12 or 6/15) and lack of binocularity (stereoacuity > or = 200 sec arc), 1400 drivers who had had an accident during their 70th year were compared with 2636 controls randomly selected from the 30,000 70-year-old drivers who had had no accident during the same time.(More)
A retrospective study shows several factors that influence the ultimate prognosis of fracture-dislocations of the hip. The magnitude of the initial injury worsens the prognosis as far as functional recovery and residual pain are concerned. The most difficult cases are those with anterior and posterior fractures of the acetabulum. The quality of reduction is(More)
The primary non-invasive treatment of anal-carcinoma by radiochemotherapy (RCT) is generally accepted although prospective randomised trials have not been finished yet. Finally the complex interaction of the radiotherapy and the commonly used cytotoxic agents 5-FU and Mitomycin-C are unknown, besides the radiosensitization. In the radiotherapy quality(More)