Frederick Y. Kazama

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The serum-borne lysophospholipid mediators sphingosine 1-phosphate (Sph-1-P) and lysophosphatidic acid (LPA) have been shown to be released from activated platelets and to act on endothelial cells. In this study, we employed the repeated lipid extraction (under alkaline and acidic conditions), capable of detecting Sph-1-P, LPA, and possibly structurally(More)
The kinetics of inactivation of a bacteriophage by potassium ferrate were studied with the F-specific RNA-coliphage Q beta. Inactivation in phosphate buffer (pH 6, 7 and 8) containing ferrate could be described by Hom's model. The inactivation rate depended on the pH. However, the relative effects of ferrate concentration and exposure time on inactivation(More)
Acid phosphatase distribution in the biflagellate zoospores of a marine fungus Thraustochytrium, resembling T. motivum Goldstein, was examined utilizing ultrastructural cytochemistry. Acid phosphatase activity was found in the Golgi saccules, Golgi vesicles, multivesicular bodies, endoplasmic reticulum, and autophagic vacuoles. Extensive autolysis of(More)
The major difference between freeze-etched illuminated and non-illuminatedPhlyctochytrium zoospores was in the plasmalemma. The illuminated spores had abundant 15–18 nm freeze fracture particles on the PF surface of the plasmalemma in a region external to the rumposomal complex. Non-illuminated spores show fewer and smaller (6–12 nm) freeze fracture(More)