Frederick Lorenz

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Chick embryos ranging from the stage of first cleavage to that of about 700 cells were removed from the oviduct and examined by transmission electron microscopy. Beneath the cell membrane is yolk-free cortical region containing microfilaments. Beneath this lies cytoplasm which contains yolk spheres which are graded in size, the dorsal ones being smaller(More)
Regression of left ventricular hypertrophy in hemodialysis patients is possible. Left ventricular hypertrophy represents the major risk factor for cardiac morbidity and mortality. Therefore, their regression is mandatory. Since the causes of uremia-associated left ventricular hypertrophy are multifactorial, various therapeutic options can be considered:(More)
The long standing question of the source of methylglyoxal formed in glycolyzing tissues was considered. Nonbiological studies, made with chemical model systems, made evident that the formation of methylglyoxal from dihydroxyacetone and from Dr.-glyceraldehyde under physiological conditions of pH and temperature is catalyzed by Tris and by certain polyvalent(More)
A new experimental procedure for the production of arteriosclerosis in the bird is described. The subcutaneous implantation of diethylstilbestrol by means of which a sustained increase in the concentration of cholesterol, phospholipid, and neutral fat can be readily established, is shown to induce atherosclerosis of the aorta. The atherosclerosis has been(More)