Frederick C. Wong

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Embryonic stem cell (ESC) self-renewal efficiency is determined by the level of Nanog expression. However, the mechanisms by which Nanog functions remain unclear, and in particular, direct Nanog target genes are uncharacterized. Here we investigate ESCs expressing different Nanog levels and Nanog(-/-) cells with distinct functionally inducible Nanog(More)
We present a study of the architectural requirements and scalability of the NAS Parallel Benchmarks. Through direct measurements and simulations, we identify the factors which affect the scalability of benchmark codes on two relevant and distinct platforms; a cluster of workstations and a ccNUMA SGI Origin 2000. We find that the benefit of increased global(More)
The rostrocaudal (head-to-tail) axis is supplied by populations of progenitors at the caudal end of the embryo. Despite recent advances characterising one of these populations, the neuromesodermal progenitors, their nature and relationship to other populations remains unclear. Here we show that neuromesodermal progenitors are a single Sox2(low)T(low) entity(More)
A cDNA encoding a eukaryotic translation initiation factor 5A (eIF-5A) homolog in heterotrophic dinoflagellate Crypthecodinium cohnii (CceIF-5A) was isolated through random sequencing of a cDNA library. The predicted amino acid sequence possesses the 12 strictly conserved amino acids around lysine 52 (equivalent to lysine 50 or 51 in other eukaryotes). A(More)
With the growing importance of fast system area networks in the parallel community, it is becoming common for message passing programs to run in multi-programming environments. Competing sequential and parallel jobs can distort the global coordination of communicating processes. In this paper, we describe our implementation of MPI using implicit information(More)
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