Fred W Lafferty

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The clinical spectrum of 100 consecutive cases of surgically proved primary hyperparathyroidism treated from 1974 through 1978 was analyzed. Their laboratory test results were compared with 64 cases of other form of hypercalcemia using multivariate discriminant analysis. The clinical spectrum has dramatically shifted during the past three decades from renal(More)
Controversy continues as to which method of measuring bone mineral density (BMD) best detects osteoporosis and best correlates with fractures of the spine, hip and elsewhere. To answer these questions the prevalence of fractures was carefully determined among 90 subjects (70 with osteoporosis, 6 with mild primary hyperparathyroidism, 1 with osteomalacia and(More)
We studied long-term morbidity after parathyroid surgery for primary hyperparathyroidism in 100 patients and compared it with the long-term morbidity of medical follow-up from the literature. The surgical treatment of primary hyperparathyroidism was associated with negative results of neck explorations, persistent hypercalcemia, recurrent hypercalcemia,(More)
The long-term effects of estrogen replacements in post-menopausal women were assessed in 61 estrogen-treated and 63 control subjects followed prospectively for 3-16 yr (mean 8.6 yr). A loss of height of 1.3 cm (1/2") or more developed with twice the frequency among control as among estrogen-replaced subjects, with the major difference appearing after 65 yr(More)