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Medical diagnosis and therapy planning at modern intensive care units (ICUs) have been refined by the technical improvement of their equipment. However, the bulk of continuous data arising from complex monitoring systems in combination with discontinuously assessed numerical and qualitative data creates a rising information management problem at neonatal(More)
Real-time systems for monitoring and therapy planning, which receive their data from on-line monitoring equipment and computer-based patient records, require reliable data. Data validation has to utilize and combine a set of fast methods to detect, eliminate, and repair faulty data, which may lead to life-threatening conclusions. The strength of data(More)
OBJECTIVE To investigate if the factor V Leiden mutation (F-V-LM) and/or the prothrombin gene G 20210 A variant (P-G20210A-V) are risk factors for acute stroke in Austrian children. PATIENTS 33 children with acute ischemic stroke documented by computer tomography and/or magnetic resonance imaging of the brain were enrolled in an open multicenter survey.(More)
Transcutaneous oxygen (TcPo2) and carbon dioxide (TcPco2) tensions were compared with arterial values in 23 children aged 4 months to 14 years, all requiring some form of respiratory support, but not in shock. Electrodes were placed on the upper chest and were heated to 45 degrees C. For TcPo2 and arterial oxygen (Pao2) a tight linear correlation over the(More)
Transcutaneous partial pressures of oxygen (PtcO2) and carbon dioxide (PtcCO2) were measured in 16 haemodynamically stable patients of a paediatric intensive care unit and were compared with simultaneously measured arterial partial pressures (PaO2 and PaCO2). For the transcutaneous measurement a sensor temperature of 44 degrees C was chosen, blood gas(More)
This paper addresses a method of therapy planning applicable in the absence of an appropriate curve-fitting model. It incorporates knowledge about data points, data intervals, and expected qualitative trend description to arrive at unified qualitative descriptions of parameters (temporal data abstraction). Our approach benefits from derived qualitative(More)
This paper addresses two important components of our knowledge–based system, VIE–VENT, a monitoring and therapy planning system for artificially ventilated newborn infants: data validation and data abstraction. VIE–VENT is specifically designed for practical use under real–time constraints in Neonatal Intensive Care Units (NICUs). Monitoring includes(More)
Therapy planning benefits from derived qualitative values or patterns which can be used for recommending therapeutic actions as well as for assessing the effectiveness of these actions within a certain period. Dealing with highfrequency data, shifting contexts, and different expectations of the development of parameters requires particular temporal(More)
The aim of our study was to evaluate the reliability of pulse oximetry in detecting both hyper- and hypoxaemic states and to create clinically feasible alarm limits. A total of 792 readings of a pulse oximeter and corresponding values of arterial oxygen tension from 146 (79M, 67F) artificially ventilated preterm newborns with indwelling umbilical artery(More)
Silvia Miksch, Yuval Shahar, Werner Horn, Christian Popow, Franz Paky, Peter Johnson 1 Vienna University of Technology, Institute of Software Technology, Resselgasse 3/188, A-1040 Vienna, Austria, email: silvia@ifs.tuwien.ac.at 2 Section on Medical Informatics, Stanford University, Stanford, CA 94 305 5479, USA email: shahar@smi.stanford.edu 3 Austrian(More)