Franz Kappel

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We consider the problem of estimating a modeling parameter using a weighted least squares criterion (,) = ∑ =1 1 () 2 (() − (,)) 2 for given data by introducing an abstract framework involving generalized measurement procedures characterized by probability measures. We take an optimal design perspective, the general premise (illustrated via examples) being(More)
This article examines the functional and clinical impact of time delays that arise in human physiological systems, especially control systems. An overview of the mathematical and physiological contexts for considering time delays will be illustrated, from the system level to cell level, by examining models that incorporate time delays. This examination will(More)
In this article, we discuss the design and implementation of a receding horizon control (RHC) which will be used to represent the control for the baroreceptor loop in the human cardiovascular system (CVS). This control will be applied to a model of the CVS developed in a previous work by Kappel and Peer. In that earlier work, a linear quadratic control(More)