Franz Günter Sander

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The aryl hydrocarbon (Ah) receptor binds various environmental pollutants, such as polycyclic aromatic hydrocarbons, heterocyclic amines, and polychlorinated aromatic compounds (dioxins, dibenzofurans, and biphenyls), and mediates the carcinogenic effects of these agents. The complementary DNA and part of the gene for an 87-kilodalton human protein that is(More)
The paper demonstrates how to generate an individual 3D volume model of a human single-rooted tooth using an automatic workflow. It can be implemented into finite element simulation. In several computational steps, computed tomography data of patients are used to obtain the global coordinates of the tooth's surface. First, the large number of geometric data(More)
BACKGROUND Ketamine shows, besides its general anesthetic effect, a local anesthetic-like action that is due to blocking of peripheral nerve sodium currents. In this study, the stereoselectivity of the blocking effects of the ketamine enantiomers S(+) and R(-) was investigated in sodium and potassium channels in peripheral nerve membranes. METHODS Ion(More)
A scanning electron microscopy study of possible root resorptions and their localization after application of continuous forces of different magnitudes was conducted. Twelve upper first premolars, indicated for extraction, were previously intruded with constant forces. The teeth were divided into 3 groups: 1. non-moved control teeth, 2. continuous force(More)
In 20 subjects the neuromuscular activity during the day was divided into six different activities and recorded. In the case of typical application of the SII appliance for 4 hours in the afternoon and the free organization of this time by the patient himself, most of the time fell into the area "intellectual activity" followed by the area "manual(More)
The use of accessory intermaxillary elastic traction or magnets during bite jumping appliance therapy marks a significant improvement in patient treatment. The use of interarch traction results in 100% mouth closure during the night, which is independent of the patient's sleeping position. During the night the guide pegs are subjected to almost no stress,(More)
INTRODUCTION The main objectives of this study were to generate individual finite element models of extracted human upper first premolars, and to simulate the distribution of the hydrostatic pressure in the periodontal ligament (PDL) of these models for evaluation of the risk of root resorption. METHODS The individual extracted teeth were from a previous(More)
AIM The aim of this investigation was to employ a new in-vitro testing system for manual toothbrushes in order to distinguish the more effective from those less so for dental care during fixed appliance treatment. MATERIALS AND METHODS The testing apparatus consisted of a sliding carriage able to execute a horizontal brushing movement, and a row of(More)
In twelve patients, 43 nocturnal sleep investigations were carried out telemetrically. These investigations were aimed at contributing towards answering the questions of how large the interocclusal distance is during the night, whether there is a correlation with the growth pattern, and whether this interocclusal distance can be changed by using Class II(More)
We succeeded in developing a retraction spring that shows virtually constant retracting forces up to an activation of about 4.5 mm through the use of various non-linear materials. Compared to all other known retraction springs, an actual bodily retraction is possible over a large range for the first time. The clinical application requires no more than one(More)