Frans J. Th. Wackers

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Electrocardiographic (ECG) gated single-photon emission tomography (SPET) allows for simultaneous assessment of myocardial perfusion and left ventricular (LV) function. Presently 8-frame per cardiac cycle ECG gating of SPET images is standard. The aim of this study was to compare the effect of 8-frame and 16-frame gated SPET on measurements of LV volumes(More)
AIMS To determine if perfusion stress echocardiography (PSE) with Imagify (perflubutane polymer microspheres) is comparable to stress perfusion imaging using (99m)Tc single photon emission computed tomography (SPECT) for coronary artery disease (CAD) detection. PSE is a novel technique for evaluating myocardial perfusion. RAMP (real-time assessment of(More)
Diastolic dysfunction can be diagnosed on equilibrium radionuclide angiocardiography (ERNA) by a low peak filling rate (PFR) in the setting of a normal left ventricular ejection fraction (LVEF). The authors evaluated the relationship between diastolic dysfunction, LVEF, and end-diastolic volume (EDV). A total of 408 predominantly asymptomatic patients with(More)
Kosa I, Ficaro EP, Schwaiger M. Attenuation-corrected 99mTctetrofosmin single-photon emission computed tomography in the detection of viable myocardium: Comparison with positron emission tomography using 18F-fluorodeoxyglucose. J Am Coll Cardiol 1998; 32:927–935. 11. Gallowitsch HJ, Unterweger O, Mikosch P, Kresnik E. Sykora J, Grimm G, Lind P.(More)
The underlying principle of determining ventricular function by radionuclide imaging is that radiotracer photon fluxes detected with a gamma camera are proportional to volume of imaged radioactive object. Changes in volume can be measured as, changes in count densities. Although this principle is in general valid, there are technical and equipment(More)
As a consequence of acute ischemia and reperfusion in patients with acute ST elevation myocardial infarction, calcium overload inside myocytes not only affects myocardial contraction, relaxation, and myocyte recovery following reperfusion, but also may be related to myocyte necrosis and fatal arrhythmia. MCC-135 is the first in a new class of agents that(More)
BACKGROUND Clopidogrel is a platelet adenosine receptor antagonist which can influence coronary vascular tone and thus can potentially interfere with myocardial perfusion imaging. We investigated whether clopidogrel can hamper the diagnosis of ischemia in patients undergoing myocardial perfusion testing. METHODS Data from a database of 6349 myocardial(More)
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