Frank von Sonnenburg

Learn More
OBJECTIVE To describe the evolution of the HIV-1 epidemic among women attending antenatal clinics in four different geographic areas within two rural regions with differing intervention intensity in south-west Tanzania. DESIGN AND METHODS Age-specific trends in HIV-1 seroprevalence among antenatal clinic attendees in four distinct geographic areas of(More)
The efficacy of chloroquine in the treatment of uncomplicated falciparum malaria in Africa is heavily compromised by high levels of drug resistance. The occurrence of active site mutations in the Plasmodium falciparum multi drug resistance-gene 1 (pfmdr1) has been associated with development of resistance to chloroquine. This study investigates the(More)
The prevalence of dengue antibodies was determined in the Attapeu region of South Laos with 225 blood samples collected from mostly febrile patients during the rainy season August - October 2001. An IgM capture ELISA was positive for one (0.4%) sample, while 177 (79%) samples were positive in an indirect IgG ELISA. Of the positive IgG samples, 20 (11.3%)(More)
Failures of mefloquine prophylaxis in travellers returning from Africa have been reported repeatedly. Non-compliance to chemoprophylaxis is considered to be a major factor for failure. Only few reports on mefloquine prophylaxis failure in sub-Saharan Africa were able to report blood levels of the drug that were sufficient for prophylactic effectiveness. We(More)
BACKGROUND About 50 million people travel each year from industrialized countries to destinations in the tropics and subtropics. Among them, there are more than 2 million minors traveling. Although their number is increasing constantly, data on health risks during travel are limited. METHODS This study analyzed demographic, travel, and clinical data of(More)
Seventy-one anti-hepatitis A virus (HAV) negative volunteers were immunized against hepatitis A. An inactivated hepatitis A vaccine (HAVRIX, SmithKline Beecham), derived from tissue cell cultures, at single doses of 720 ELISA units was used following a schedule of vaccinations at month 0.1 and 6. The vaccines were tested for the presence of HAV antibodies 1(More)
Objectives: The goal was to determine vaccination rates and predictors of vaccination behaviour of pediatricians in Munich, Germany. Methods: Standardised questionnaires were sent to all 133 office-based pediatricians in Munich. Results: 97 questionnaires (73%) were returned completely. Vaccination rates were sufficiently against diphtheria, tetanus, and(More)
The resistance of 2,314 bacterial strains from 1968 to 1972 was investigated drawing on case histories from the Munich University Urological Clinic. Using the disc-diffusion method 12,160 sensitivity tests were conducted with these strains against gentamicin, co-trimoxazole, ampicillin, tetracycline and chloramphenicol. The material was compiled from 35,000(More)
Im Zuge der stetigen Zunahme des Ferntourismus sind in den letzten Jahren einige Ausbrüche von Schistosomiasis bei Reisenden, Militärpersonal und dauerhaft im Ausland tätigen Europäern beobachtet worden. Um Risikofaktoren einer Schistosomiasis festzustellen, wurden die Reiseanamnesen, klinischen, serologischen und parasitologischen Daten von 62 deutschen(More)
Eine 33-jährige Patientin aus dem Libanon stellte sich mit rezidivierenden Hämoptysen, subfebrilen Temperaturen, Belastungsdyspnoe, Abgeschlagenheit, Gewichtsabnahme und Pruritus vor. Die serologischen und bildgebenden Untersuchungen führten zu der Diagnose einer zystischen Echinokokkose mit Lungenbeteilung. Da die Patientin eine chirurgische Intervention(More)
  • 1