Frank Wuest

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The three-step radiosynthesis of N-succinimidyl 4-[(18)F]fluorobenzoate ([(18)F]SFB) was adapted to a remotely controlled synthesis module. After optimization of the reaction conditions, the final [(18)F]SFB was obtained in decay-corrected radiochemical yields of 34-38% (related to [(18)F]fluoride; n=12) within a synthesis time of 68 min. The radiochemical(More)
This work involves the production, processing and imaging of the short-lived, rarely used positron emission tomography (PET) radionuclide technetium-94m (94mTc). Our procedures are an extension of methods reported in the literature and are detailed within. A key modification was the development of a single step that combines purification and concentration(More)
AIM Replacement of the ecologically harmful solvent Freon 11 (CFCl(3)) by chloroform for the module-assisted preparation of 6-[(18)F]fluoro-L-DOPA based on the electrophilic radiofluorodestannylation of the precursor N-formyl-3,4-di-tert-butoxycarbonyloxy-6-(trimethylstannyl)-L-phenylalanine ethyl ester. MATERIALS, METHODS The TRACERlab Fx FDOPA module(More)
The combination of return-to-zero differential quadrature phase-shift keying with polarization-division multiplex, a 16-ary modulation scheme, allows for ultimate spectral efficiency. We raise -band fiber capacity with phase-shift keying transmission beyond previously reported figures, achieving forward-error correction limit performance over four fiber(More)
Polarization division multiplex (PolDM) doubles the data rate in existing trunk lines without need for additional optical bandwidth. In the presence of dispersion compensation, polarization mode dispersion (PMD) limits the achievable transmission length. PMD tolerance of standard binary intensity modulation or non-return-to-zero coding has already been(More)