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The family Rhizobiaceae contains plant-associated bacteria with critical roles in ecology and agriculture. Within this family, many Rhizobium and Sinorhizobium strains are nitrogen-fixing plant mutualists, while many strains designated as Agrobacterium are plant pathogens. These contrasting lifestyles are primarily dependent on the transmissible plasmids(More)
Partial degradation products of sodium hyaluronate produced by the action of testicular hyaluronidase induced an angiogenic response (formation of new blood vessels) on the chick chorioallantoic membrane. Neither macromolecular hyaluronate nor exhaustively digested material had any angiogenic potential. Fractionation of the digestion products established(More)
5 of 8 infarcted human myocardial tissues were shown to contain an angiogenesis factor which resembles that obtained from solid tumours. The concentration of angiogenesis factor, measured by radioimmunoassay, was similar to that in tumours. It is suggested that the myocardial-infarct angiogenesis factor modulates collateral enlargement or ingrowth of new(More)
[1] Currently a cosmic ray cloud connection (CRC) hypothesis is subject of an intense controversial debate. It postulates that galactic cosmic rays (GCR) intruding the Earth's atmosphere influence cloud cover. If correct it would have important consequences for our understanding of climate driving processes. Here we report on an alternative and stringent(More)
We have investigated the formation and early growth of atmospheric secondary aerosol particles building on atmospheric measurements. The measurements were part of the QUEST 2 campaign which took place in spring 2003 in Hyytï aï a (Finland). During the campaign numerous new aerosol particle formation events occurred of which 15 5 were accompanied by gaseous(More)
Targeted anti-HER2 therapy has greatly improved the prognosis for many breast cancer patients. However, treatment for HER2 negative disease is currently still selected from a multitude of untargeted chemotherapeutic treatment options. A predictive test was developed using patient-derived spheroids to identify the most effective therapy for patients with(More)
Freshly formed atmospheric aerosol particles are neither large enough to efficiently scatter incoming solar radiation nor able to act as cloud condensation nuclei. As the particles grow larger, their hygroscopicity determines the limiting size after which they are important in both of the aforementioned processes. The condensing species result-5 ing in(More)
From a synopsis of field, laboratory and model studies at T >205K as well as from the field experiments POLSTAR at T <205K we derive a general picture of the partitioning of nitric acid (HNO 3) in cirrus clouds and a new hypothesis on the uptake of HNO 3 on ice particles: 5 A substantial part of nitric acid remains in the gas phase under cirrus cloud(More)