Frank Kastrau

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In the present study, we were interested in the neurofunctional representations of ambiguity processing by using functional magnetic resonance imaging (fMRI). Twelve right-handed, healthy adults aged between 21 and 29 years (6 male, 6 female) underwent an ambiguity resolution task with 4 different conditions (dominant vs. non-dominant; dominant vs.(More)
The aim of the present study was to determine whether processing of syntactic word information (lemma) is subserved by the same neural substrate as processing of conceptual or word form information (lexeme). We measured BOLD responses in 14 native speakers of German in three different decision tasks, each focussing specifically on one level of lexical(More)
Neuroimaging research on the neurobiology of chronic PTSD (posttraumatic stress disorder) has revealed structural and functional alterations primarily affecting areas of the medial temporal lobe (hippocampus, amygdala, and parahippocampal gyrus) and the frontal cortex known to be associated with the disorder. Using functional magnetic resonance imaging(More)
Neurofunctional alterations in acute posttraumatic stress disorder (PTSD) and changes thereof during the course of the disease are not well investigated. We used functional magnetic resonance imaging to assess the functional neuroanatomy of emotional memory in surgical patients with acute PTSD. Traumatic (relative to non-traumatic) memories increased neural(More)
Primary progressive aphasia is a rare disease characterised by slow deterioration of language, which remains the leading symptom whereas other cognitive functions such as memory, orientation, judgement, and visual-spatial skills are relatively spared and mostly not affected until 5 to 7 years after disease onset. Structural imaging displays atrophy of the(More)
Previous neuroimaging studies showed that correct resolution of lexical ambiguity relies on the integrity of prefrontal and inferior parietal cortices. Whereas prefrontal brain areas were associated with executive control over semantic selection, inferior parietal areas were linked with access to modality-independent representations of semantic memory. Yet(More)
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