Frank Jackson

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One of the more promising automatic storage reclamation techniques, generation scavenging, suffers poor performance if many objects live for a fairly long time and then die. We have investigated the severity of this problem by simulating a two-generation scavenger using traces taken from actual 4-h sessions. There was a wide variation in the sample runs,(More)
  • Roz Laing, Taisei Kikuchi, Axel Martinelli, Isheng J Tsai, Robin N Beech, Elizabeth Redman +21 others
  • 2013
The small ruminant parasite Haemonchus contortus is the most widely used parasitic nematode in drug discovery, vaccine development and anthelmintic resistance research. Its remarkable propensity to develop resistance threatens the viability of the sheep industry in many regions of the world and provides a cautionary example of the effect of mass drug(More)
Anthelmintic drug resistance in livestock parasites is already widespread and in recent years there has been an increasing level of anthelmintic drug selection pressure applied to parasitic nematode populations in humans leading to concerns regarding the emergence of resistance. However, most parasitic nematodes, particularly those of humans, are difficult(More)
The genomes of numerous parasitic nematodes are currently being sequenced, but their complexity and size, together with high levels of intra-specific sequence variation and a lack of reference genomes, makes their assembly and annotation a challenging task. Haemonchus contortus is an economically significant parasite of livestock that is widely used for(More)
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  • David J Buttle, Jerzy M Behnke, Yvonne Bartley, Hany M Elsheikha, David J Bartley, Martin C Garnett +4 others
  • 2011
BACKGROUND The cysteine proteinases in papaya latex have been shown to have potent anthelmintic properties in monogastric hosts such as rodents, pigs and humans, but this has not been demonstrated in ruminants. METHODS In two experiments, sheep were infected concurrently with 5,000 infective larvae of Haemonchus contortus and 10,000 infective larvae of(More)
We have inherited from G. E. Moore the following, I think attractive, analysis of what we ought to do in terms of what is good and bad. Gx (x ought to F in certain circumstances C if and only if F-ing is that action, of the actions that x can perform in C, that produces the most good and the least bad). 1 The analysis proposes a reduction of one moral(More)
Each week every student should do the assigned reading and write a short (2-3 double-spaced pages; no more than 750 words) paper focused on some aspect of the reading. Please e-mail your papers to me at the above address no later than noon of each Monday. There is one book that you should purchase for the seminar if you do not already own it: Saul Kripke's(More)