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BACKGROUND AND PURPOSE Stroke is a significant economic, social, and medical problem worldwide. This retrospective follow-up study aimed to review the pattern, types, and case fatality of stroke in Nigeria. METHODS Records of all stroke patients admitted into Ogun State University Teaching Hospital (OSUTH), Sagamu, from December 1993 to November 2003 were(More)
BACKGROUND The burden of cerebrovascular disease in developing countries is projected to be on the rise. However, data on the current epidemiology of stroke in Africa are sparse. METHODS Using a 3-staged method, we conducted a door-to-door study of stroke in an urban, mixed-income community in Lagos, Nigeria. We used a modification of the WHO protocol in(More)
BACKGROUND Stroke is a leading cause of death worldwide and a major contributor to global disease burden. Although epidemiologic information from a community perspective is important in determining the magnitude of the burden in specific regions, and directing equitable distribution of health resources, data on the incidence of stroke in developing(More)
Clinical distinction between cerebral haemorrhage (CH) and cerebral infarction (CI) is important in the management of stroke patients in areas where CT scan facility is lacking or access limited by cost and distance. This distinction is necessary in our environment where an increasing proportion of patients are suspected to have haemorrhagic stroke. This(More)
BACKGROUND There is evidence of an association between mediators of inflammation, particularly C-reactive protein (CRP), and outcome of acute ischaemic stroke. This provides a potential opportunity for interventions aimed at improving outcome. There is sparse data exploring the role of inflammatory markers such as CRP and stroke outcome in Africans. The(More)
OBJECTIVE to review cases of myasthenia gravis at the Lagos University Teaching Hospital. METHODS features of 27 cases of myasthenia gravis seen at the Neurology outpatient clinic of the Lagos University Teaching Hospital between January 1995 and December 2000 were reviewed using a uniform protocol. RESULTS peak age incidence was in the third decade,(More)
OBJECTIVE To determine the predictors of 30-day intra-hospital case fatality rate in patients with first-ever acute ischaemic stroke, attending a tertiary care hospital in Western Nigeria. STUDY DESIGN A cross-sectional observational study. PLACE AND DURATION OF STUDY This study was conducted at the Lagos University Teaching Hospital, Lagos, Nigeria(More)
OBJECTIVES Hypercholesterolaemia is a risk factor for cardiovascular diseases. Tocotrienols reportedly possess hypocholesterolaemic activity. This study examined the effect of tocotrienols (T3) in TOCOVIDTM Suprabio TM on serum lipids. Patients and Methods :A randomised (2:1), open-label study of patients with mild hypercholesterolaemia (= 5.18mmol/L to(More)
We investigated the 1-year prevalence, clinical features and mode of treatment of headache in medical students of the University of Lagos, Nigeria, using a self-administered headache questionnaire. Headache prevalence was 46.0% and was significantly higher in women than in men (62.8% vs. 34.1%). Prevalence of tension-type headache was higher than that of(More)
Records of 349 tetanus patients, aged 10 years and above, admitted to the Lagos University Teaching Hospital, Nigeria, between 1990 and 1999 were reviewed. The male:female ratio was 1.98:1, and the ages were between 10 and 88 years, with a mean age of 29.8 years. The overall case fatality rate (CFR) of tetanus was 36.96% (33.19% for men and 44.44% for(More)