Frank Hässler

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The review presented here describes the state of the art of pharmacological treatment of aggression in subjects with mental retardation (MR) summing up results for both, children and adults. In general, psychopharmacological treatment of disruptive behavior in individuals with MR is similar to the treatment in subjects without MR. Compared to individuals(More)
BACKGROUND Given the dosing limitations of methylphenidate short-acting preparations in treating ADHD, galenics with longer release of the substance were developed mainly to avoid drug intake during school hours. OBJECTIVES This investigation was conducted to assess the efficacy and the duration of action of a new extended-release formulation of(More)
Internalizing and externalizing problems based on Youth Self-Report (YSR) were investigated in an empirical sample of 371 students at the age of 13 until 18 years from common secondary and vocational schools in Rostock (Mecklenburg-Western Pomerania) in 2000/2001. Considering syndromes in comparison with other german and international empirical studies,(More)
In this study, we examined the influence of both reward and penalty on delay decisions in subjects with ADHD. Eighteen 6- to 13-year-old boys with ADHD (combined or hyperactive-impulsive subtype) along with age- and IQ-matched control participants performed a memory game. If the children were successful at the game, they could choose between a small(More)
INTRODUCTION Aggression is frequently observed in children and adolescents with attention-deficit/hyperactivity disorder (ADHD). The aim of this study was to assess the efficacy with regard to oppositional and aggressive behavior of a new long-acting methylphenidate preparation (Medikinet retard, MPH-MR), with equal portions of the immediate-release and the(More)
OBJECTIVES Adult ADHD is characterised by a plethora of comorbid conditions. However, the comorbidity of schizophrenia and ADHD does not seem to be a typical feature and is therefore under-researched. OBJECTIVE To identify adult patients with schizophrenia and comorbid ADHD and compare their symptomatology with schizophrenic patients without ADHD. (More)
Localized developmental disturbances of school skills such as dyslexia, acalculia and speech and language disorders are common child and adolescent psychiatric disorders. Every second child develops comorbid mental disorders such as disturbance of social behaviour and hyperkinetic, emotional, anxiety or obsessive-compulsive disorder. For this reason, a(More)
The paper reviews international research on sexual abuse prevention for individuals with mental retardation and programs implemented in Germany. Using Pubmed, PsycINFO, and various search engines, 263 studies and 128,080 search results for programs were retrieved, of which twelve international studies and six national programs met several inclusion(More)
OBJECTIVE Disruptive or challenging behavior problems pose a threat to children and adolescents with intellectual disabilities and their caregivers. Psychopharmacological treatment is mostly studied with new-generation antipsychotics and has been criticized for adverse side effects. This study examined the effect of the classic antipsychotic zuclopenthixol.(More)