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Contribution of vasogenic and cellular edema to traumatic brain swelling measured by diffusion-weighted imaging.
The contribution of brain edema to brain swelling in cases of traumatic brain injury remains a critical problem. The authors believe that cellular edema, the result of complex neurotoxic events, isExpand
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A realistic brain tissue phantom for intraparenchymal infusion studies.
OBJECT The goal of this study was to validate a simple, inexpensive, and robust model system to be used as an in vitro surrogate for in vivo brain tissues in preclinical and exploratory studies ofExpand
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Characterization of edema by diffusion-weighted imaging in experimental traumatic brain injury.
The objective of this study was to use diffusion-weighted magnetic resonance imaging (DWI) to help detect the type of edema that develops after experimental trauma and trauma coupled with hypotensionExpand
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The permissive nature of blood brain barrier (BBB) opening in edema formation following traumatic brain injury.
The contribution of blood brain barrier opening to traumatic brain edema is not known. This study compares the course of traumatic BBB disruption and edema formation, with the hypothesis that theyExpand
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Biphasic pathophysiological response of vasogenic and cellular edema in traumatic brain swelling.
The objective of this study was to quantify the temporal water content changes and document the type of edema (cellular versus vasogenic) that is occurring during both the acute and the late stagesExpand
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In vitro and in vivo studies of single-walled carbon nanohorns with encapsulated metallofullerenes and exohedrally functionalized quantum dots.
Single-walled carbon nanohorns (SWNHs) are new carbonaceous materials. In this paper, we report the first successful preparation of SWNHs encapsulating trimetallic nitride template endohedralExpand
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Magnetic resonance imaging-monitored acute blood-brain barrier changes in experimental traumatic brain injury.
The authors posit that cellular edema is the major contributor to brain swelling in diffuse head injury and that the contribution of vasogenic edema may be overemphasized. The objective of this studyExpand
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Comparison of NAA measures by MRS and HPLC.
This work investigates the accuracy of an in vivo estimation of absolute N-acetyl aspartate (NAA) concentrations by magnetic resonance spectroscopy (MRS) using cerebral water as an internal referenceExpand
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Acute blood-brain barrier changes in experimental closed head injury as measured by MRI and Gd-DTPA.
The objective of this study was to determine the early time course of blood-brain barrier (BBB) changes in diffuse closed head injury (CHI) and to what extent BBB is affected by secondary insult. TheExpand
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cis-3, 4′, 5-Trimethoxy-3′-aminostilbene disrupts tumor vascular perfusion without damaging normal organ perfusion
PurposeTargeting tumor vasculature by colchicine site microtubule inhibitors is a new approach in cancer therapy. Here we investigate cis-3, 4′, 5-trimethoxy-3′-aminostilbene (stilbene 5c) in itsExpand
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