Frank Aumann

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We present Monte Carlo (MC) simulations of the stretching of a single chromatin fiber. The model approximates the DNA by a flexible polymer chain with Debye-Hückel electrostatics and uses a two-angle zigzag model for the geometry of the linker DNA connecting the nucleosomes. The latter are represented by flat disks interacting via an attractive Gay-Berne(More)
We present recent studies on the structure and dynamics of monoand oligonucleosomes, using fluorescence correlation spectroscopy and fluorescence resonance energy transfer (FRET). The effect of salt concentration, linker histone H1 and histone acetylation on the structure of monoand trinucleosomes reconstituted on nucleosome positioning sequences was(More)
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