Frank A. Quinn

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During a normal menstrual cycle, serum levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), estradiol, and progesterone can vary widely between cycles for the same woman, as well as between different woman. Reliable reference values based on the local population are important for correct interpretation of laboratory results. The purpose(More)
BACKGROUND Maternal thyroid dysfunction has been associated with a variety of adverse pregnancy outcomes. Laboratory measurement of thyroid function plays an important role in the assessment of maternal thyroid health. However, occult thyroid disease and physiologic changes associated with pregnancy can complicate interpretation of maternal thyroid function(More)
BACKGROUND Thyroid disorders are common, often go unrecognized, and when left untreated, can have serious public health implications. Dietary and ethnic differences are known to influence thyroid function. However, comparatively few studies have examined the prevalence of autoimmune thyroid disease (AITD) and thyroid function test (TFT) reference intervals(More)
Undiagnosed thyroid disease is a common problem with significant public health implications. This is especially true during pregnancy, when the health of both the mother and the developing child can be adversely affected by abnormal maternal thyroid function. Measurement of serum thyroid stimulating hormone (TSH) and thyroid peroxidase antibodies (TPO-Ab)(More)
OBJECTIVES A comprehensive set of age- and gender-specific pediatric reference intervals is essential for accurate interpretation of laboratory tests in a pediatric setting. DESIGN AND METHODS 1459 serum/plasma from children attending select outpatient clinics and deemed to be metabolically stable, were collected from five age groups; 0-12 months, 1-5(More)
Total protein-bound carbohydrates (PBC), as neutral hexoses, were quantified in the plasma of C3H mice as a function of time relative to whole-body exposure to either monoenergetic 14-MeV neutrons or mixed gamma-neutron radiations delivered at a rate of approximately 20 rads/ min. The reported doses, 365 to 530 rads, were those which yielded survivors under(More)
The objective of this study was to evaluate the reproducibility and accuracy of internal fit using Cerec 3D CAD/CAM (computer aided design/computer aided manufacturing) all-ceramic crowns and to investigate the proximal contact point areas between the crowns and neighbouring teeth, in terms of location and the presence or absence of contact. A total of 48(More)
BACKGROUND The IFCC Committee for Standardization of Thyroid Function Tests aims at equivalence of laboratory test results for free thyroxine (FT4) and thyrotropin (TSH). OBJECTIVES This report describes the phase III method comparison study with clinical samples representing a broad spectrum of thyroid disease. The objective was to expand the feasibility(More)