Francois Bessueille

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We present a technology for the fabrication of three dimensional microfluidic channels in optically transparent substrates consisting of polymers with different properties. The microstructures are fabricated using polymer replication techniques with a view to the production of microfluidic devices with characteristics suitable for biomedical applications.(More)
A technique for microcontact printing of thiols in liquid media is presented. Elastomeric poly(dimethyl siloxane) stamps are used to pattern gold surfaces with thiol-based self-assembled monolayers. The liquid (water in this case) has been used as an incompressible support and, advantageously, also acts as a medium in which alkylthiol ink molecules are(More)
Cobaltabisdicarbollide-doped polypyrrole (PPy-[Co(C 2 B 9 H 11) 2 ]) nanostructures have been produced by directed, potentiostatic electropolymerisation using a patterned combination of conducting and insulating thiols, 4-aminothiophenol and octadecylmercaptan respectively. The different conducting characters of both SAMs guides the PPy-[Co(C 2 B 9 H 11) 2(More)
A sensitive electrochemical molecularly-imprinted sensor was developed for the detection of aflatoxin B1 (AFB1), by electropolymerization of p-aminothiophenol-functionalized gold nanoparticles in the presence of AFB1 as a template molecule. The extraction of the template leads to the formation of cavities that are able to specifically recognize and bind(More)
Thanks to their properties, Single-Walled carbon nanotubes (SWNT) open a new way to the fabrication of Immunosensors with the particularity to amplify the response signal from antibody–antigen interaction and to improve the Immunosensors characteristics. In this context, two new impedimetric immunosensors were developed by immobilizing antibody on(More)
The increase in the number of investigations into biomedical interactions with structured substrates has produced a necessity for transparent, micro-and nanostructured surfaces. To facilitate research, it must be possible to use these structured surfaces in conjunction with established culturing and imaging apparatus available within a biomedical(More)
This paper describes friction experiments and pull-off force measurements using atomic force microscopy, between a non-functionalised silicon probe and a 2.5 m diameter CH 3 and COOH terminated thiol self assembled monolayer pattern. The pattern is micro-contact printed onto a gold-coated silicon wafer, in air, at room temperature, with a relative humidity(More)
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