Francisco Vera

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BACKGROUND Taxanes are among the most active drugs for the treatment of metastatic breast cancer, and, as a consequence, they have also been studied in the adjuvant setting. METHODS After breast cancer surgery, women with lymph node-positive disease were randomly assigned to treatment with fluorouracil, epirubicin, and cyclophosphamide (FEC) or with FEC(More)
PURPOSE This study was conducted to relate the histological diagnosis of chronic inflammatory periapical lesions with the radiographic images of these lesions. MATERIALS AND METHODS A total of 70 biopsy specimens obtained during periapical surgery were stained with hematoxylin and eosin and examined under a microscope. Histological analysis established(More)
BACKGROUND Rifabutin has been found to be effective in multi-resistant patients after various treatment cycles for Helicobacter pylori (HP) infection, but it has not been analysed as a second-line treatment. Therefore, we seek to compare the effectiveness of a treatment regimen including rifabutin versus conventional quadruple therapy (QT). METHODS Open(More)
PURPOSE To relate the histologic diagnosis and radiographic size with the prognosis of 70 biopsies obtained via periapical surgery. MATERIALS AND METHODS Seventy biopsies obtained during periapical surgery were histologically analyzed following curettage of the tissue, establishing the diagnosis as either apical granuloma, radicular cyst, or scar tissue.(More)
PURPOSE Cherubism is an uncommon fibro-osseous disorder of the jaws that presents with varying degrees of involvement and a tendency toward spontaneous remission. Lesions are characterized by replacement of bone with fibrovascular tissue containing abundant multinucleated giant cells. We attempted to study the relationships among the degree of cherubism,(More)
There is clear value, in both industrial and government settings, derived from performing statistical analyses that, in effect, integrate data in multiple, distributed databases. However, the barriers to actually integrating the data can be substantial or even insurmountable. Corporations may be unwilling to share proprietary databases such as chemical(More)
A prospective study of 81 heart transplant (HT) patients was carried out in order to evaluate the evolution of brain natriuretic peptide (BNP) levels in HT patients and compare them with the degree of rejection as determined by endomyocardial biopsy. All patients were subjected to endomyocardial biopsy (532), and determination of BNP and creatinine levels(More)
Syndromic surveillance has, so far, considered only simple models for Bayesian inference. This paper details the methodology for a serious, scalable solution to the problem of combining symptom data from a network of U.S. hospitals for early detection of disease outbreaks. The approach requires high-end Bayesian modeling and significant computation, but the(More)
Reliable surveillance models are an important tool in public health because they aid in mitigating disease outbreaks, identify where and when disease outbreaks occur, and predict future occurrences. Although many statistical models have been devised for surveillance purposes, none are able to simultaneously achieve the important practical goals of good(More)