Francisco Tinahones

José María Moreno-Navarrete3
José Manuel Fernández-Real3
Chong Yew Tan2
3José María Moreno-Navarrete
3José Manuel Fernández-Real
2Chong Yew Tan
2Samuel Virtue
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  • Mónica Ballesteros, Inmaculada Simón, Joan Vendrell, Victoria Ceperuelo-Mallafré, Ramon M. Miralles, Gerard Albaiges +2 others
  • 2011
OBJECTIVE To analyze the relationship between maternal adiponectin (mAdiponectin) and cord blood adiponectin (cbAdiponectin) multimeric forms (high molecular weight [HMW], medium molecular weight [MMW], and low molecular weight [LMW]) in a cohort of gestational diabetes mellitus (GDM) and normal glucose-tolerant (NGT) pregnant women. RESEARCH DESIGN AND(More)
This paper aims to study the effects of the oxidative stress induced by quality and quantity of dietary fat on cellular senescence. Twenty elderly subjects consumed three diets, each for 4 weeks: a saturated fatty acid diet (SFA), a low-fat and high-carbohydrate diet (CHO-ALA), and a Mediterranean diet (MedDiet) enriched in monounsaturated fatty acid(More)
  • Matteo Serino, José Manuel Fernández-Real, Eduardo García Fuentes, Maribel Queipo-Ortuño, José María Moreno-Navarrete, Álex Sánchez +2 others
  • 2013
The role of the gut microbiota in the induction of metabolic diseases has now been increasingly recognized worldwide. Indeed, a specific gut microbiota has been shown to characterize lean versus obese phenotypes both in humans and mice. We have also recently demonstrated that a precise gut microbiota is associated with the host's responsiveness to a(More)
  • Marina R. Pulido, Alberto Diaz-Ruiz, Yolanda Jiménez-Gómez, Socorro Garcia-Navarro, Francisco Gracia-Navarro, Francisco Tinahones +4 others
  • 2011
Lipid droplets (LDs) are organelles that coordinate lipid storage and mobilization, both processes being especially important in cells specialized in managing fat, the adipocytes. Proteomic analyses of LDs have consistently identified the small GTPase Rab18 as a component of the LD coat. However, the specific contribution of Rab18 to adipocyte function(More)
BACKGROUND Alternative macrophages (M2) express the cluster differentiation (CD) 206 (MCR1) at high levels. Decreased M2 in adipose tissue is known to be associated with obesity and inflammation-related metabolic disturbances. Here we aimed to investigate MCR1 relative to CD68 (total macrophages) gene expression in association with adipogenic and(More)
UNLABELLED It is well known that the adult human thymus degenerates into fat tissue; however, it has never been considered as a potential source of angiogenic factors. Recently, we have described that this fat (TAT) produces angiogenic factors and induces human endothelial cell proliferation and migration, indicating its potential angiogenic properties. (More)
  • Chong Yew Tan, Samuel Virtue, Steven Murfitt, Lee D Roberts, Yi Hui Phua, Martin Dale +4 others
  • 2016
This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the(More)
  • Chong Yew Tan, Samuel Virtue, Steven Murfitt, Lee D. Robert, Yi Hui Phua, Martin Dale +4 others
  • 2015
The non-essential fatty acids, C18:1n9, C16:0, C16:1n7, C18:0 and C18:1n7 account for over 75% of fatty acids in white adipose (WAT) triacylglycerol (TAG). The relative composition of these fatty acids (FA) is influenced by the desaturases, SCD1-4 and the elongase, ELOVL6. In knock-out models, loss of SCD1 or ELOVL6 results in reduced Δ9 desaturated and(More)