Francisco Ramirez-Lafita

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A solid phase radioimmunoassay was used to quantify levels of antibodies to vimentin intermediate filaments (VIF) of the cytoskeleton in sera from patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Significantly higher levels of these antibodies were found in 52% of the SLE sera studied, compared to 6% in RA sera and 10% of sera(More)
Intervention: Dose reduction (n = 121) or usual care (n = 59). In the dose-reduction group, time between injections was increased every 3 months and then discontinued. Treatment returned to the last effective interval if a flare occurred. If the flare persisted, treatment was increased to the shortest interval. If the flare still persisted, treatment was(More)
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