Francisco Lissoni

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Cross-sectional studies typically find positive correlations between free availability of scientific articles (‘open access’) and citations. Using a number of instruments as plausible sources of exogeneous variation, we find no evidence for a causal effect of open access on citations. We provide theory and evidence suggesting that authors of higher quality(More)
The antihypertensive efficacy, the hemodynamic effects and the tolerability of a new slow-release nicardipine (SR-Nic) formulation, capsules containing 40 mg of active drug, have been tested in a randomized, double-blind placebo (P)-controlled study. Thirty mild-to-moderate essential hypertensives were enrolled and after a one-week single-blind placebo(More)
The effects of aging on the results of prolonged drug-free tilt testing were studied in 175 consecutive patients with unexplained syncope divided into 3 groups: 59 patients < 40 years old; 57 patients between 40 and 60 years; and 59 patients > 60 years old. Tilt-induced vaso-vagal syncope occurred respectively in 17 (29%), 20 (35%), and 18 patients (31%) in(More)
In a single-blind, placebo-controlled study the acute and chronic antianginal effects of three slow-release (SR) new formulations of isosorbide dinitrate (ISDN 60, 80, 100 mg) have been comparatively evaluated in a group of aged affected by chronic stable effort-induced angina. Compared to placebo, overall the active dose paritetically improved the effort(More)
We reexamine the widely held belief that free availability of scientific articles increases the number of citations they receive. Since open access is relatively more attractive to authors of higher quality papers, regressing citations on open access and other controls yields upwardbiased estimates. Using an instrumental variable approach, we find no(More)
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